Anti-aging Theories Part II
Waste Accumulation Theory
The waste accumulation theory of aging states that in the course
of a life span cells produce more waste than they can properly
eliminate. The waste includes various toxins that when
accumulated to a certain level they can interfere with normal
cell function and ultimately kill the cell.
Limited Number of Cell Divisions Theory
This theory is concerned with the number of cell divisions
directly affected by the accumulations of the cell’s waster
products. As more wastes accumulate over time the cells quickly
degenerate thus causing aging and ultimately death.
Hayflick Limit Theory
Dr. Hayflick theorized that the aging process was controlled by
a biological clock contained within each living cell. Studies
done in 1961 concluded that human fibroblast cells (lung, skin,
muscle, heart) have a limited life span. They divide
approximately 50 times over a period of years and then suddenly
stop. They also concluded nutrition seemed to have an effect on
the rate of cell division. Final conclusion of this theory
states that improper functioning of cells and loss of cells in
organs and tissues may be responsible for the effects of aging.
Death Hormone Theory (DECO)
Brain cells or neurons are unlike other cells in that they do
not replicate. At birth we have roughly 12 billion of them and
over a life time about 10 percent die out. Dr. Donner Denckle
speculated that as we age the pituitary begins to release DECO
which inhibits the ability of cells to use thyroxine. Thyrozine
is a hormone produced by the thyroid-governing basal metabolism,
which is the rate at which cells convert food to energy. The
metabolic rate brings on and accelerates the process of aging.
Thymic-Stimulating Theory
Dr. Alan Goldstein says “the thymus is the master gland of the
immune systems.” The size of the gland continues to reduce and
shrink to round three grams by age 60. Scientists are
investigating the possibility that the disappearance of the
thymus contributes to the aging process by weakening the body’s
immune system.
Mitochondrial Theory
This is the free radical theory is supported by directed
experimental observations of Mitochondrial aging. Our primary
source of energy comes from ATP. Mitochondria are the
energy-producing organelles in the cells that produce ATP. They
produce cell energy by a process that leads to forming
potentially damaging free radicals. Evidence seems to tell us
that various kinds of accumulated DNA damage over time
contribute to disease. New research in mitochondrial repair
could play an important role in the fight against aging.
Errors and Repairs Theory
Dr. Leslie Orgel suggested in 1963 that because the “machinery
for making protein in cells is so essential, an error in that
machinery could be catastrophic.” Since the system is incapable
of always making perfect repairs on these molecules, the
accumulation of flawed molecules can cause disease and other age
changes to occur.
Redundant DNA Theory
This theory is similar to the error-and-repairs theory in that
it also blames errors accumulating in genes for age changes. A
difference is that as these errors accumulate the reserve
genetic sequences of identical DNA that take over until the
system is work out.
Source: The American Academy of Anti-Aging Medicine
Disclaimer: These statements have not been evaluated by the Food
and Drug Administration. The information in this article is not
intended to diagnose, treat, cure or prevent any disease. All
health concerns should be addressed by a qualified health care
professional.
Waste Accumulation Theory
The waste accumulation theory of aging states that in the course
of a life span cells produce more waste than they can properly
eliminate. The waste includes various toxins that when
accumulated to a certain level they can interfere with normal
cell function and ultimately kill the cell.
Limited Number of Cell Divisions Theory
This theory is concerned with the number of cell divisions
directly affected by the accumulations of the cell’s waster
products. As more wastes accumulate over time the cells quickly
degenerate thus causing aging and ultimately death.
Hayflick Limit Theory
Dr. Hayflick theorized that the aging process was controlled by
a biological clock contained within each living cell. Studies
done in 1961 concluded that human fibroblast cells (lung, skin,
muscle, heart) have a limited life span. They divide
approximately 50 times over a period of years and then suddenly
stop. They also concluded nutrition seemed to have an effect on
the rate of cell division. Final conclusion of this theory
states that improper functioning of cells and loss of cells in
organs and tissues may be responsible for the effects of aging.
Death Hormone Theory (DECO)
Brain cells or neurons are unlike other cells in that they do
not replicate. At birth we have roughly 12 billion of them and
over a life time about 10 percent die out. Dr. Donner Denckle
speculated that as we age the pituitary begins to release DECO
which inhibits the ability of cells to use thyroxine. Thyrozine
is a hormone produced by the thyroid-governing basal metabolism,
which is the rate at which cells convert food to energy. The
metabolic rate brings on and accelerates the process of aging.
Thymic-Stimulating Theory
Dr. Alan Goldstein says “the thymus is the master gland of the
immune systems.” The size of the gland continues to reduce and
shrink to round three grams by age 60. Scientists are
investigating the possibility that the disappearance of the
thymus contributes to the aging process by weakening the body’s
immune system.
Mitochondrial Theory
This is the free radical theory is supported by directed
experimental observations of Mitochondrial aging. Our primary
source of energy comes from ATP. Mitochondria are the
energy-producing organelles in the cells that produce ATP. They
produce cell energy by a process that leads to forming
potentially damaging free radicals. Evidence seems to tell us
that various kinds of accumulated DNA damage over time
contribute to disease. New research in mitochondrial repair
could play an important role in the fight against aging.
Errors and Repairs Theory
Dr. Leslie Orgel suggested in 1963 that because the “machinery
for making protein in cells is so essential, an error in that
machinery could be catastrophic.” Since the system is incapable
of always making perfect repairs on these molecules, the
accumulation of flawed molecules can cause disease and other age
changes to occur.
Redundant DNA Theory
This theory is similar to the error-and-repairs theory in that
it also blames errors accumulating in genes for age changes. A
difference is that as these errors accumulate the reserve
genetic sequences of identical DNA that take over until the
system is work out.
Source: The American Academy of Anti-Aging Medicine
Disclaimer: These statements have not been evaluated by the Food
and Drug Administration. The information in this article is not
intended to diagnose, treat, cure or prevent any disease. All
health concerns should be addressed by a qualified health care
professional.
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